NSES Content Standard F  
Science in Personal and Social Perspectives: Personal health 
Grades K-4, page 140 

Different substances can damage the body and how it functions. Such substances include tobacco, alcohol, over-the-counter medicines, and illicit drugs. Students should understand that some substances, such as prescription drugs, can be beneficial, but that any substance can be harmful if used inappropriately. 
 
 
Benchmark 6E The Human Organism: Physical Health
Grades K-2, page 144
Some things people take into their bodies from the environment can hurt them.

Benchmark 6E The Human Organism: Physical Health
Grades 3-5, page 144
Tobacco, alcohol, other drugs, and certain poisons in the environment (pesticides, lead) can harm human beings and other living things.