NSES Content Standard F 
Science in Personal and Social Perspectives: Personal and community health 
Grades 9-12, page 197 

An individual's mood and behavior may be modified by substances. The modification may be beneficial or detrimental depending on the motives, type of substance, duration of use, pattern of use, level of influence, and short- and long-term effects. Students should understand that drugs can result in physical dependence and can increase the risk of injury, accidents, and death. 

Benchmark 6E The Human Organism: Physical Health
Grades 3-5, page 144
Tobacco, alcohol, other drugs, and certain poisons in the environment (pesticides, lead) can harm human beings and other living things.