Benchmark 4A
The Physical Setting: The Universe
Grades 9-12, page 65

Mathematical models and computer simulations are used in studying evidence from many sources in order to form a scientific account of the universe.

NSES Content Standard G 
History and Nature of Science: Nature of science 
Grades 5-8, page 171 
Scientists formulate and test their explanations of nature using observation, experiments, and theoretical and mathematical models. Although all scientific ideas are tentative and subject to change and improvement in principle, for most major ideas in science, there is much experimental and observational confirmation. Those ideas are not likely to change greatly in the future. Scientists do and have changed their ideas about nature when they encounter new experimental evidence that does not match their existing explanations. 

NSES Content Standard A 
Science as Inquiry: Understanding about scientific inquiry 
Grades 9-12, page 175 
Mathematics is essential in scientific inquiry. Mathematical tools and models guide and improve the posing of questions, gathering data, constructiong explanations and communicating results.