Benchmark 10I
Historical Perspectives: Discovering Germs
Grades 6-8, page 257

Pasteur wanted to find out what causes milk and wine to spoil. He demonstrated that spoilage and fermentation occur when microorganisms enter from the air, multiply rapidly, and produce waste products. After showing that spoilage could be avoided by keeping germs out or by destroying them with heat, he investigated animal diseases and showed that microorganisms were involved. Other investigators later showed that specific kinds of germs caused specific diseases.
 

See Content Standard G History and Nature of Science (grades 9-12): Historical Perspectives